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If you're not failing occasionally, you're not pushing hard enough.
The biggest regret in life is giving up what should not be given up easily, and stubbornly persisting in what should not be persisted.
On developing company culture: "Part of company culture is path-dependent—it's the lessons you learn along the way."
The total amount of suffering per year in the natural world is beyond all decent contemplation.
You have to believe in the reality of the world and the reality of the people in it.