The truth is you don't know what is going to happen tomorrow. Life is a crazy ride, and nothing is guaranteed.
Profitability and responsibility are not opposites; they are two sides of the same coin.
"The only thing to do with good advice is to pass it on. It is never of any use to oneself."
A goal is not always meant to be reached, it often serves simply as something to aim at.
Nowadays, particularly in the United States, if you meet someone at the bottom of society, they may unkindly be described as a "loser." There's a real difference between an unfortunate and a loser, and that shows 400 years of evolution in society and our belief in who is responsible for our lives. It's no longer the gods, it's us. We're in the driving seat.