The act of writing is an act of optimism. You would not take the trouble to do it if you felt it didn't matter.
The greatest obstacle to being heroic is the doubt whether one may not be going to prove one's self a fool; the truest heroism is to resist the doubt, and the profoundest wisdom to know when it ought to be resisted, and when it be obeyed.
科学中的每一个发现都是离治愈更近的一步。